Calentamiento de nanopartículas de oro inducido por excitación fotónica y multifotónica
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Resumen
Se evalúa la temperatura generada por nanopartículas de oro (AuNPs) al ser irradiadas con luz láser para su utilidad en terapia fototérmica plasmónica fotónica o multifotónica. Las AuNPs fueron sintetizadas por el método de Turkevitch y caracterizadas por técnicas espectroscópicas. La irradiación se realiza con un láser Nd:YAG, a longitudes de onda de 532 y 1 064 nm, frecuencias de repetición 5, 10 y 15 Hz durante 210 s. La temperatura fue medida con un termopar tipo K acoplado a una tarjeta Arduino UNO®. Las AuNPs muestran tamaños de 20.7 + 0.2 nm, forma esférica y un máximo de absorción UV-Vis en 520.16 + 0.93 nm. La irradiación a 1 064 nm exhibe mayor incremento de temperatura en 3.4, 1.9, y 1.2 veces más que a 532 nm a las respectivas frecuencias.
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Ali, M. R. K., Wu, Y., & El-Sayed, M. A. (2019). Gold-Nanoparticle-Assisted Plasmonic Photothermal Therapy Advances Toward Clinical Application [Review-article]. Journal of Physical Chemistry C, 123(25), 15375-15393. https://doi.org/10.1021/acs.jpcc.9b01961
Golovynskyi, S., Golovynska, I., Stepanova, L. I., Datsenko, O. I., Liu, L., Qu, J., & Ohulchanskyy, T. Y. (2018). Optical windows for head tissues in near-infrared and short-wave infrared regions: Approaching transcranial light applications. Journal of Biophotonics, 11(12), e201800141. https://doi.org/10.1002/jbio.201800141
Huang, X., & El-Sayed, M. A. (2010). Gold nanoparticles: Optical properties and implementations in cancer diagnosis and photothermal therapy. In Journal of Advanced Research. https://doi.org/10.1016/j.jare.2010.02.002
Huh, J. H., Lee, J., & Lee, S. (2018). Comparative study of plasmonic resonances between the roundest and randomly faceted au nanoparticles-on-mirror cavities. ACS Photonics, 5(2), 413-421. https://doi.org/10.1021/acsphotonics.7b00856
Kasten, B. B., Liu, T., Nedrow-Byers, J. R., Benny, P. D., & Berkman, C. E. (2013). Targeting prostate cancer cells with PSMA inhibitor-guided gold nanoparticles. Bioorganic & Medicinal Chemistry Letters, 23(2), 565-568. https://doi.org/10.1016/j.bmcl.2012.11.015
Liu, Y., Crawford, B. M., & Vo-Dinh, T. (2018). Gold nanoparticles-mediated photothermal therapy and immunotherapy. Immunotherapy, 10(13), 1175-1188. https://doi.org/10.2217/imt-2018-0029
Liu, Y., Bhattarai, P., Dai, Z., & Chen, X. (2019). Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer. Chemical Society Reviews, 48(7), 2053-2108. https://doi.org/10.1039/C8CS00618K
Luna-Gutiérrez, M., Ferro-Flores, G., Ocampo-García, B., Jiménez-Mancilla, N., Morales-Avila, E., De Leõn-Rodríguez, L., & Isaac-Olivé, K. (2012). 177Lu-labeled monomeric, dimeric and multimeric RGD peptides for the therapy of tumors expressing α(ν)β(3) integrins. Journal of Labelled Compounds and Radiopharmaceuticals, 55(4), 140-148. https://doi.org/10.1002/jlcr.2910
Ma, Y. C., Zhu, Y. H., Tang, X. F., Hang, L. F., Jiang, W., Li, M., Khan, M. I., You, Y. Z., & Wang, Y. C. (2019). Au nanoparticles with enzyme-mimicking activity-ornamented ZIF-8 for highly efficient photodynamic therapy. Biomaterials Science, 7(7), 2740-2748. https://doi.org/10.1039/c9bm00333a
Panikkanvalappil, S. R., Hooshmand, N., & El-Sayed, M. A. (2017). Intracellular assembly of nuclear-targeted gold nanosphere enables selective plasmonic photothermal therapy of cancer by shifting their absorption wavelength toward near-infrared region. Bioconjugate Chemistry, 28(9), 2452-2460. https://doi.org/10.1021/acs.bioconjchem.7b00427
Paschotta, R. (2019). Multiphoton absorption. RP Photonics Encyclopedia. Retrieved from https://www.rp-photonics.com/multiphoton_absorption.html
Riley, R. S., & Day, E. S. (2017). Gold nanoparticle-mediated photothermal therapy: Applications and opportunities for multimodal cancer treatment. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(4), e1449. https://doi.org/10.1002/wnan.1449
Sivasubramanian, M., Chuang, Y. C., & Lo, L. W. (2019). Evolution of nanoparticle-mediated photodynamic therapy: From superficial to deep-seated cancers. Molecules, 24(3). https://doi.org/10.3390/molecules24030520
Szepes, L., & Tarczay, G. (1999). Photoelectron Spectrometers. Encyclopedia of Spectroscopy and Spectrometry, 1822-1830. https://doi.org/10.1006/RWSP.2000.0235
Zhang, D., Wu, T., Qin, X., Qiao, Q., Shang, L., Song, Q., Yang, C., & Zhang, Z. (2019). Intracellularly generated immunological gold nanoparticles for combinatorial photothermal therapy and immunotherapy against tumor. Nano Letters, 19(9), 6635-6646. https://doi.org/10.1021/acs.nanolett.9b02903
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