Pathogenic Bacteria and Ticks: A Bad Combination for Sustainable Livestock Farming Bacterias patógenas y garrapatas: una mala combinación para la ganadería sustentable
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jul 14, 2026
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https://doi.org/10.30878/ces.v33n0a77
Main Article Content
Hugo Aguilar-Díaz
http://orcid.org/0000-0002-6497-6462
Maria del Socorro López-López
http://orcid.org/0000-0001-6441-426X
Estrella Lizbeth Castillo-Díaz
http://orcid.org/0009-0003-3135-299X
Rosa Estela Quiroz-Castañeda
http://orcid.org/0000-0002-1099-2440
http://orcid.org/0000-0002-6497-6462
Maria del Socorro López-López
http://orcid.org/0000-0001-6441-426X
Estrella Lizbeth Castillo-Díaz
http://orcid.org/0009-0003-3135-299X
Rosa Estela Quiroz-Castañeda
http://orcid.org/0000-0002-1099-2440
Resumen
En esta revisión, bajo el enfoque de la vision "Una Salud", se propone el desarrollo de vacunas como
estrategia que promueve la salud animal y contribuye a mantener el equilibrio ecológico para un
manejo sostenible de los recursos naturales. En este sentido, los factores incontrolables como las
enfermedades animales, requieren investigación cientifica para identificar soluciones y desarrollar
vacunas o medicamentos de producción nacional que favorezcan la salud del ganado. Las propuestas
actuales se basan en la vacunología reversa para el diseño de vacunas miltiepítopo tales como las
desarrolladas contra Brucella melitensis y Mycoplasma hyopneumoniae y evaluadas en animales
modelo. Por lo que, este tipo de vacunas son una estrategia novedosa con potencial para controlar
enfermedades en el sector veterinario.
Article Details
Como citar
AGUILAR-DÍAZ, Hugo et al.
Pathogenic Bacteria and Ticks: A Bad Combination for Sustainable Livestock Farming.
CIENCIA ergo-sum, [S.l.], v. 33, jul. 2026.
ISSN 2395-8782.
Disponible en: <https://cienciaergosum.uaemex.mx/article/view/26337>. Fecha de acceso: 18 ago. 2026
doi: https://doi.org/10.30878/ces.v33n0a77.
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Espacio del divulgador
Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.
Citas
Aguilar-Díaz, H., Nava-Castro, K. E., Escobedo, G., Domínguez-Ramírez, L., García-Varela, M., Del Río-Araiza, V. H., Palacios-Arreola, M. I., & Morales-Montor, J. (2018). A novel progesterone receptor membrane component (PGRMC) in the human and swine parasite Taenia solium: Implications to the host-parasite relationship. Parasites and Vectors, 11(1), 1–11. https://doi.org/10.1186/s13071-018-2703-1
Aguilar-Díaz, H., Quiroz-Castañeda, R. E., Díaz-Esquivel, I. G., Cossío-Bayúgar, R., & Miranda-Miranda, E. (2023). A Novel Rhipicephalus microplus Estrogen Related Receptor (RmERR), a Molecular and In Silico Characterization of a Potential Protein Binding Estrogen. Microorganisms, 11(9). https://doi.org/10.3390/microorganisms11092294
Bahrami, A. A., Payandeh, Z., Khalili, S., Zakeri, A., & Bandehpour, M. (2019). Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein. International Reviews of Immunology, 38(6), 307–322. https://doi.org/10.1080/08830185.2019.1657426
Brayton, K. A., Kappmeyer, L. S., Herndon, D. R., Dark, M. J., Tibbals, D. L., Palmer, G. H., McGuire, T. C., & Knowles, D. P. (2005). Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences of the United States of America, 102(3), 844–849. https://doi.org/10.1073/pnas.0406656102
Cangussu, A. S. R., Mariúba, L. A. M., Lalwani, P., Pereira, K. D. E. S., Astolphi-Filho, S., Orlandi, P. P., Epiphanio, S., Viana, K. F., Ribeiro, M. F. B., Silva, H. M., Marinho, C. R. F., & Nogueira, P. A. (2018). A hybrid protein containing MSP1a repeats and Omp7, Omp8 and Omp9 epitopes protect immunized BALB/c mice against anaplasmosis. Veterinary Research, 49(1), 6. https://doi.org/10.1186/s13567-018-0503-4
Deplazes-Zemp, A. (2018). ‘Genetic resources’, an analysis of a multifaceted concept. Biological Conservation, 222, 86–94. https://doi.org/https://doi.org/10.1016/j.biocon.2018.03.031
FAO-ONU. (2024). FAO. https://www.fao.org/livestock-environment/es
Gray, J. S., Dautel, H., Estrada-Peña, A., Kahl, O., & Lindgren, E. (2009). Effects of Climate Change on Ticks and Tick-Borne Diseases in Europe. Interdisciplinary Perspectives on Infectious Diseases, 2009, 593232. https://doi.org/10.1155/2009/593232
Hornok, S., Foldvari, G., Elek, V., Naranjo, V., Farkas, R., & de la Fuente, J. (2008). Molecular identification of Anaplasma marginale and rickettsial endosymbionts in blood-sucking flies (Diptera: Tabanidae, Muscidae) and hard ticks (Acari: Ixodidae). Veterinary Parasitology, 154(3–4), 354–359. https://doi.org/10.1016/j.vetpar.2008.03.019
Jorge, S., & Dellagostin, O. A. (2017). The development of veterinary vaccines: a review of traditional methods and modern biotechnology approaches. Biotechnology Research and Innovation, 1(1), 6–13. https://doi.org/https://doi.org/10.1016/j.biori.2017.10.001
Kocan, K. M., Blouin, E. F., & Barbet, A. F. (2000). Anaplasmosis control. Past, present, and future. Annals of the New York Academy of Sciences, 916, 501–509. https://doi.org/10.1111/j.1749-6632.2000.tb05329.x
Kocan, K. M., de la Fuente, J., Blouin, E. F., Coetzee, J. F., & Ewing, S. a. (2010). The natural history of Anaplasma marginale. Veterinary Parasitology, 167(2–4), 95–107. https://doi.org/http://dx.doi.org/10.1016/j.vetpar.2009.09.012
Kumar Ghosh, A., & Jacobs-Lorena, M. (n.d.). Surface-expressed enolases of Plasmodium and other pathogens.
Lebov, J., Grieger, K., Womack, D., Zaccaro, D., Whitehead, N., Kowalcyk, B., & MacDonald, P. D. M. (2017). A framework for One Health research. One Health (Amsterdam, Netherlands), 3, 44–50. https://doi.org/10.1016/j.onehlt.2017.03.004
Lockwood, S., Voth, D. E., Brayton, K. a., Beare, P. a., Brown, W. C., Heinzen, R. a., & Broschat, S. L. (2011). Identification of Anaplasma marginale type IV secretion system effector proteins. PLoS ONE, 6(11), e27724. https://doi.org/10.1371/journal.pone.0027724
OIE, W. O. for A. H. (2015). Bovine Anaplasmosis. http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.04.01_BOVINE_ANAPLASMOSIS.pdf
Pagani, T. D., Guimarães, A. C. R., Waghabi, M. C., Corrêa, P. R., Kalume, D. E., Berrêdo-Pinho, M., Degrave, W. M., & Mendonça-Lima, L. (2019). Exploring the potential role of moonlighting function of the surface-associated proteins from mycobacterium bovis bcg moreau and pasteur by comparative proteomic. Frontiers in Immunology, 10(April). https://doi.org/10.3389/fimmu.2019.00716
Quiroz-Castañeda, R. E., Aguilar-Díaz, H., Coronado-Villanueva, E., Catalán-Ochoa, D. I., & Amaro-Estrada, I. (2024). Molecular Identification and Bioinformatics Analysis of Anaplasma marginale Moonlighting Proteins as Possible Antigenic Targets. Pathogens, 13(10). https://doi.org/10.3390/pathogens13100845
Quiroz Castañeda, R. E., Amaro Estrada, I., & Rodríguez Camarillo, S. D. (2016). Anaplasma marginale: Diversity, Virulence, and Vaccine Landscape through a Genomics Approach. BioMed Research International, 2016, 9032085. https://doi.org/10.1155/2016/9032085
Tembo, S., Collins, N. E., Sibeko-Matjila, K. P., Troskie, M., Vorster, I., Byaruhanga, C., & Oosthuizen, M. C. (2018). Occurrence of tick-borne haemoparasites in cattle in the Mungwi District, Northern Province, Zambia. Ticks and Tick-Borne Diseases, 9(3), 707–717. https://doi.org/https://doi.org/10.1016/j.ttbdis.2018.02.004
Vanegas, G., Quiñones, W., Carrasco-López, C., Concepción, J. L., Albericio, F., & Avilán, L. (2007). Enolase as a plasminogen binding protein in Leishmania mexicana. Parasitology Research, 101(6), 1511–1516. https://doi.org/10.1007/s00436-007-0668-7
WHO. (2020). WHO, World Health Organization. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance-publications?healthtopics=b6bd35a3-cf4f-4851-8e80-85cb0068335b&publishingoffices=aeebab07-3d0c-4a24-b6ef-7c11b7139e43&healthtopics-hidden=true&publishingoffices-hidden=true
Xue, S., Seo, K., Yang, M., Cui, C., Yang, M., Xiang, S., Yan, Z., Wu, S., Han, J., Yu, X., Li, Y., & Jin, X. (2021). Mycoplasma suis Alpha-Enolase Subunit Vaccine Induces an Immune Response in Experimental Animals. Vaccines, 9(12), 18–20. https://doi.org/10.3390/vaccines9121506
Aguilar-Díaz, H., Quiroz-Castañeda, R. E., Díaz-Esquivel, I. G., Cossío-Bayúgar, R., & Miranda-Miranda, E. (2023). A Novel Rhipicephalus microplus Estrogen Related Receptor (RmERR), a Molecular and In Silico Characterization of a Potential Protein Binding Estrogen. Microorganisms, 11(9). https://doi.org/10.3390/microorganisms11092294
Bahrami, A. A., Payandeh, Z., Khalili, S., Zakeri, A., & Bandehpour, M. (2019). Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein. International Reviews of Immunology, 38(6), 307–322. https://doi.org/10.1080/08830185.2019.1657426
Brayton, K. A., Kappmeyer, L. S., Herndon, D. R., Dark, M. J., Tibbals, D. L., Palmer, G. H., McGuire, T. C., & Knowles, D. P. (2005). Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences of the United States of America, 102(3), 844–849. https://doi.org/10.1073/pnas.0406656102
Cangussu, A. S. R., Mariúba, L. A. M., Lalwani, P., Pereira, K. D. E. S., Astolphi-Filho, S., Orlandi, P. P., Epiphanio, S., Viana, K. F., Ribeiro, M. F. B., Silva, H. M., Marinho, C. R. F., & Nogueira, P. A. (2018). A hybrid protein containing MSP1a repeats and Omp7, Omp8 and Omp9 epitopes protect immunized BALB/c mice against anaplasmosis. Veterinary Research, 49(1), 6. https://doi.org/10.1186/s13567-018-0503-4
Deplazes-Zemp, A. (2018). ‘Genetic resources’, an analysis of a multifaceted concept. Biological Conservation, 222, 86–94. https://doi.org/https://doi.org/10.1016/j.biocon.2018.03.031
FAO-ONU. (2024). FAO. https://www.fao.org/livestock-environment/es
Gray, J. S., Dautel, H., Estrada-Peña, A., Kahl, O., & Lindgren, E. (2009). Effects of Climate Change on Ticks and Tick-Borne Diseases in Europe. Interdisciplinary Perspectives on Infectious Diseases, 2009, 593232. https://doi.org/10.1155/2009/593232
Hornok, S., Foldvari, G., Elek, V., Naranjo, V., Farkas, R., & de la Fuente, J. (2008). Molecular identification of Anaplasma marginale and rickettsial endosymbionts in blood-sucking flies (Diptera: Tabanidae, Muscidae) and hard ticks (Acari: Ixodidae). Veterinary Parasitology, 154(3–4), 354–359. https://doi.org/10.1016/j.vetpar.2008.03.019
Jorge, S., & Dellagostin, O. A. (2017). The development of veterinary vaccines: a review of traditional methods and modern biotechnology approaches. Biotechnology Research and Innovation, 1(1), 6–13. https://doi.org/https://doi.org/10.1016/j.biori.2017.10.001
Kocan, K. M., Blouin, E. F., & Barbet, A. F. (2000). Anaplasmosis control. Past, present, and future. Annals of the New York Academy of Sciences, 916, 501–509. https://doi.org/10.1111/j.1749-6632.2000.tb05329.x
Kocan, K. M., de la Fuente, J., Blouin, E. F., Coetzee, J. F., & Ewing, S. a. (2010). The natural history of Anaplasma marginale. Veterinary Parasitology, 167(2–4), 95–107. https://doi.org/http://dx.doi.org/10.1016/j.vetpar.2009.09.012
Kumar Ghosh, A., & Jacobs-Lorena, M. (n.d.). Surface-expressed enolases of Plasmodium and other pathogens.
Lebov, J., Grieger, K., Womack, D., Zaccaro, D., Whitehead, N., Kowalcyk, B., & MacDonald, P. D. M. (2017). A framework for One Health research. One Health (Amsterdam, Netherlands), 3, 44–50. https://doi.org/10.1016/j.onehlt.2017.03.004
Lockwood, S., Voth, D. E., Brayton, K. a., Beare, P. a., Brown, W. C., Heinzen, R. a., & Broschat, S. L. (2011). Identification of Anaplasma marginale type IV secretion system effector proteins. PLoS ONE, 6(11), e27724. https://doi.org/10.1371/journal.pone.0027724
OIE, W. O. for A. H. (2015). Bovine Anaplasmosis. http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.04.01_BOVINE_ANAPLASMOSIS.pdf
Pagani, T. D., Guimarães, A. C. R., Waghabi, M. C., Corrêa, P. R., Kalume, D. E., Berrêdo-Pinho, M., Degrave, W. M., & Mendonça-Lima, L. (2019). Exploring the potential role of moonlighting function of the surface-associated proteins from mycobacterium bovis bcg moreau and pasteur by comparative proteomic. Frontiers in Immunology, 10(April). https://doi.org/10.3389/fimmu.2019.00716
Quiroz-Castañeda, R. E., Aguilar-Díaz, H., Coronado-Villanueva, E., Catalán-Ochoa, D. I., & Amaro-Estrada, I. (2024). Molecular Identification and Bioinformatics Analysis of Anaplasma marginale Moonlighting Proteins as Possible Antigenic Targets. Pathogens, 13(10). https://doi.org/10.3390/pathogens13100845
Quiroz Castañeda, R. E., Amaro Estrada, I., & Rodríguez Camarillo, S. D. (2016). Anaplasma marginale: Diversity, Virulence, and Vaccine Landscape through a Genomics Approach. BioMed Research International, 2016, 9032085. https://doi.org/10.1155/2016/9032085
Tembo, S., Collins, N. E., Sibeko-Matjila, K. P., Troskie, M., Vorster, I., Byaruhanga, C., & Oosthuizen, M. C. (2018). Occurrence of tick-borne haemoparasites in cattle in the Mungwi District, Northern Province, Zambia. Ticks and Tick-Borne Diseases, 9(3), 707–717. https://doi.org/https://doi.org/10.1016/j.ttbdis.2018.02.004
Vanegas, G., Quiñones, W., Carrasco-López, C., Concepción, J. L., Albericio, F., & Avilán, L. (2007). Enolase as a plasminogen binding protein in Leishmania mexicana. Parasitology Research, 101(6), 1511–1516. https://doi.org/10.1007/s00436-007-0668-7
WHO. (2020). WHO, World Health Organization. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance-publications?healthtopics=b6bd35a3-cf4f-4851-8e80-85cb0068335b&publishingoffices=aeebab07-3d0c-4a24-b6ef-7c11b7139e43&healthtopics-hidden=true&publishingoffices-hidden=true
Xue, S., Seo, K., Yang, M., Cui, C., Yang, M., Xiang, S., Yan, Z., Wu, S., Han, J., Yu, X., Li, Y., & Jin, X. (2021). Mycoplasma suis Alpha-Enolase Subunit Vaccine Induces an Immune Response in Experimental Animals. Vaccines, 9(12), 18–20. https://doi.org/10.3390/vaccines9121506